Opioid Jeopardy (404)

Double jeopardy?

Jgp_201611678 389..404

In neurons and myocytes, voltage-gated Na (NaV) channels initiate membrane excitation. Shortly thereafter, fast inactivation diminishes the Na current, which allows K efflux to return the membrane to its resting potential. Inactivation kinetics cannot be described by a single time constant, but instead require a collection of relaxations whose time domains span from milliseconds to minutes (Sil...

C2sc20763j 398..404

Many biological functions require two or more enzymes working together in cascades. While many examples of protein and RNA enzyme cascades are known, few enzyme cascades containing solely DNAzymes have been reported. Herein we demonstrate the combination of an 8–17 DNAzyme with RNA cleavage activity and an E47 DNAzyme with DNA ligation activity to achieve a new function of single ribonucleotide...

393-404 Inglese

Environmental economics, which analyses the links between economic activity and environmental systems, has hypothesized that a relation which may be described as an ‘inverted U’ exists between environmental quality/pollution and pro capite income variables (Kuznets hypothesis; Kuznets, 1955). According to this hypothesis, when income begins to grow, starting from a low level, the environmental ...

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